Pathogenic Rickettsiae as Bioterrorism Agents
نویسندگان
چکیده
منابع مشابه
Pathogenic rickettsiae as bioterrorism agents.
The diseases caused by rickettsiae vary from mild to severe clinical presentations, with case fatality ranging from none to over 30%. The severity of rickettsial diseases has been associated with age, delayed diagnosis, hepatic and renal dysfunction, central nervous system abnormalities, and pulmonary compromise. Despite the variability in clinical presentations many pathogenic rickettsiae caus...
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We conducted a systematic review of the scientific literature from 1966 to 2005 to determine whether animals could provide early warning of a bioterrorism attack, serve as markers for ongoing exposure risk, and amplify or propagate a bioterrorism outbreak. We found evidence that, for certain bioterrorism agents, pets, wildlife, or livestock could provide early warning and that for other agents,...
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Multivalency plays a major role in biological processes and particularly in the relationship between pathogenic microorganisms and their host that involves protein-glycan recognition. These interactions occur during the first steps of infection, for specific recognition between host and bacteria, but also at different stages of the immune response. The search for high-affinity ligands for study...
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To the Editor: Mediannikov et al. recently reported several features common to the epidemiology of Rickettsia felis infection and malaria in Africa (1). Similar to the findings of several other recent studies in Africa (2,3), the authors diagnosed R. felis infection in febrile—and to a lesser extent in afebrile—persons by detecting R. felis DNA in human blood samples processed by highly sensiti...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2007
ISSN: 1537-6591,1058-4838
DOI: 10.1086/518147